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Flashpoint Discussion: Ebola Hemorrhagic Fever

October 13, 2014 @ 5:30 pm - 8:00 pm

| $10 - $20


Ebola Hemorrhagic Fever

 Monday, 13 October 2014 5:30 PM – 8:00 PM AMN Healthcare Boardroom 12400 High Bluff Drive, San Diego, CA 92130

Professor Erica Ollman Saphire

Co-Director, Global Virus Network Center of ExcellenceDepartment of Immunology and Microbial Science The Scripps Research Institute  

The Ebola outbreak of 2014 in West Africa has been the most devastating known, with approximately 6100 cases and 3100 deaths reported to date. The current outbreak is thought to have started in December 2013 in Guinea and has since migrated to Liberia, Sierra Leone, Nigeria and Senegal. On 30 September, a single case was confirmed in the U.S. and all efforts are being made to contain the disease. In a worst-case scenario released on September 23rd by the Centers for Disease Control and Prevention, Liberia and Sierra Leone could have a total of 21,000 cases of Ebola by September 30th and 1.4 million cases by January 20, 2015. The death rate from Ebola ranges from 50% to 90%. Burgeoning populations encroaching on shrinking forest lands and poaching wild game of potentially infected animals are often the source of such outbreaks. Risks posed by porous borders with rapid travel, combined with poor health infrastructure, rampant superstitions, and misinformation have made this outbreak tragically difficult to contain. While previous episodes of Ebola virus have been localized in rural areas and affected small numbers of people, the perfect storm seems to have been created that could spread this contagious disease worldwide. While no cures are known for Ebola, the San Diego biopharma company Mapp Pharmaceuticals has developed a potential treatment called ZMapp that is being fast-tracked by the Food and Drug Administration. What does this drug ZMapp do and how might it work? Professor Erica Ollman Saphire, molecular biologist, whose research aims to uncover the cracks in the virus’s armor, will guide us through this rapidly-evolving health threat.

Dec. 13, 2012 - San Diego, California, USA - December 13th, 2012, San Diego, California, USA. |  Erica Ollmann Saphire, Ph.D, stands in her lab at The Scripps Research Institute on Thursday in San Diego, California.  Photo by Eduardo Contreras/UT San Diego/Zuma Press. copyright 2012 UT San Diego

Erica Ollmann Saphire, Ph.D. is a Professor of Immunology and Microbial Science at The Scripps Research Institute. Her research explains how and why viruses are pathogenic and provides the roadmap for medical defense. Her team has explained how the viruses drive themselves into cells, how they suppress immune function, where human antibodies can defeat them, as well as the structure of the entire human antibody itself. A recent discovery expanded the central dogma of molecular biology by proving that certain viral proteins actually rearrange into different structures at different times for different functions. Her work has been recognized with the Presidential Early Career Award in Science and Engineering, an Investigators in the Pathogenesis of Infectious Disease and a Career Award in the Biomedical Sciences from the Burroughs Wellcome Fund, by young investigator awards from the American Society for Biochemistry and Molecular Biology and the American Society of Microbiology, and by the Surhain Sidhu award for the most outstanding contribution to the field of diffraction by a person within five years of the Ph.D. She is a Fellow of the American Academy of Microbiology, serves on the Scientific Leadership Board of the Global Virus Network and is the Director of the Viral Hemorrhagic Fever Immunotherapeutic Consortium. This organization, the VIC, united the field into a single force to understand and provide antibody therapeutics against Ebola, Marburg, Lassa and other viruses.


5:30 pm Registration and Reception

6:00 pm Presentation

7:00 pm Q&A

8:00 pm Wrap-up

Free to members registered through October 10, $10 after October 10
General Public $10 online; $20 onsite


October 13, 2014
5:30 pm - 8:00 pm
$10 - $20
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619 325 8200


AMN Healthcare
12400 High Bluff Drive
San Diego, CA 92130 United States
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